CLSI M48 PDF

CLSI M48 – Laboratory Detection and Identification of Mycobacteria, 2nd Edition, M48Ed2E

This guideline provides recommendations for medical mycobacteriology laboratories on the optimal approach for diagnosis of mycobacterial infections.

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Clinical and Laboratory Standards Institute guideline M48 – Laboratory Detection and Identification of Mycobacteria coverstopics related to laboratory diagnosis of mycobacterial infections, including safety and risk assessment, referrals, clinicalsignificance, acceptable specimen types, specimen collection, transport, and storage, specimen processing methods, microscopyfor direct detection, molecular methods for directly detecting mycobacteria in patient specimens, culture methods, contaminationissues, reporting, quality control, and conventional identification methods as they relate to mass spectrometry and genotypicprocedures. Recommendations for managing the unique challenges associated with the increasing incidence of Mycobacteriumtuberculosis and nontuberculous mycobacteria infections are included.